On Thursday 12th April, Alssundgymnasiet Sønderborg School from Denmark visited the School of Life Sciences. In the afternoon, 19 pupils took part in a workshop using Jalview to fetch DNA, RNA and protein sequences from a variety of biological databases. They aligned sequences, generated trees and viewed the 3D shape of myoglobin proteins.
On Thursday 30th November, Geoff Barton and Suzanne Duce ran the second Dundee Protein Sequence Analysis workshop of the year. The course considered the relationship between protein sequence and structure. It used JPred4 to predict protein structure from multiple alignments. Then used protein sub-family analysis in Jalview to identify functionally important regions.
A video on 'Secondary structure prediction of proteins in Jalview' has been added to our YouTube channel. JPred predicts the location of secondary structure (α-helix and β-strand) and solvent accessibility from a single sequence of multiple alignment.
There are just a handful of spaces left at the Jalview’s ‘Protein, RNA and DNA multiple sequence alignment and functional analysis’ workshop.
The course is suitable for both Jalview novices and experienced users who would like to learn more about Jalview's capabilities.
The course will cover topic such as loading, editing and saving sequences, multiple sequence alignment, creating trees, viewing annotation and features, working with 3D structures.